1-Thioglycerol AR 90% MSDS

 

Section 1: Chemical Product and Company Identification

Product Name: 1-Thioglycerol AR 90%

Catalog Codes: SLM1210

CAS#: 96-27-5

RTECS: TY8140000

TSCA: TSCA 8(b) inventory: 1-Thioglycerol AR 90%

CI#: Not available.

Synonym: Thiovanol; 3-Mercapto-1,2-propanediol;

1-Mercapto-2,3-propanediol; 1-Mercaptoglycerol;

1-Thioglycerol; alpha-Monothioglycerol; alpha-Thioglycerol;

Monothioglycerin; Thioglycerin; Thioglycerol

Chemical Name: 1,2-Propanediol, 3-mercapto-

Chemical Formula: C3-H8-O2-S

 

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

Monothioglycerol 96-27-5 100

Toxicological Data on Ingredients: Monothioglycerol: ORAL (LD50): Acute: 670 mg/kg [Rat]. DERMAL (LD50): Acute: 699.3

mg/kg [Rabbit].

 

Section 3: Hazards Identification

Potential Acute Health Effects:

Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of inhalation. Slightly hazardous in

case of ingestion.

Potential Chronic Health Effects:

Hazardous in case of skin contact (permeator).

CARCINOGENIC EFFECTS: Not available.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

 

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at

least 15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention.

Skin Contact:

In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove

contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get

medical attention.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate

medical attention.

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get

medical attention.

Serious Inhalation: Not available.

Ingestion:

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an

unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight

clothing such as a collar, tie, belt or waistband.

Serious Ingestion: Not available.

 

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: CLOSED CUP: >112.78C (235F).

Flammable Limits: Not available.

Products of Combustion: These products are carbon oxides (CO, CO2).

Fire Hazards in Presence of Various Substances:

Slightly flammable to flammable in presence of open flames and sparks, of heat.

Non-flammable in presence of shocks.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards:

When heated to decomposition it emits toxic fumes.

Container may rupture from gas generation during a fire situation. Violent stream generation or eruption may

occur upon application of direct water stream to hot liquids.

Special Remarks on Explosion Hazards: Not available.

 

Section 6: Accidental Release Measures

Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.

Large Spill:

Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by

spreading water on the contaminated surface and allow to evacuate through the sanitary system.

 

Section 7: Handling and Storage

Precautions:

Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the

residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/

vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory

equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with

skin and eyes. Keep away from incompatibles such as oxidizing agents, metals, acids.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.

 

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their

respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the

work-station location.

Personal Protection:

Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be

used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits: Not available.

 

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Viscous liquid.)

Odor: Sulfidic (Slight.)

Taste: Not available.

Molecular Weight: 108.15 g/mole

Color: Colorless to light yellow.

pH (1% soln/water): Not available.

Boiling Point: 118C (244.4F)

Melting Point: Not available.

Critical Temperature: Not available.

Specific Gravity: 1.295 (Water = 1)

Vapor Pressure: Not available.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, acetone.

Solubility:

Easily soluble in acetone.

Slightly soluble in cold water.

Insoluble in diethyl ether.

Slightly soluble in benzene.

Miscible with alcohol.

 

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability:

Excess heat (Avoid temperatures above 120 C. Product can decompose at elevated temperatures), incompatible

materials.

Incompatibility with various substances: Reactive with oxidizing agents, metals, acids.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity:

Avoid contact with oxidizing materials. Reactions with oxidizers can be violent.

Avoid contact with metals such as carbon steel.

Avoid unintended contact with strong acids.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

 

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Ingestion.

Toxicity to Animals:

Acute oral toxicity (LD50): 670 mg/kg [Rat].

Acute dermal toxicity (LD50): 699.3 mg/kg [Rabbit].

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans:

Hazardous in case of skin contact (irritant, permeator), of inhalation.

Slightly hazardous in case of ingestion.

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans:

May affect genetic material (mutagenic).

May cause adverse reproductive effects based on animal test data. No human data found

Special Remarks on other Toxic Effects on Humans:

Potential Health Effects:

Skin: Prolonged or repeated exposure may cause severe skin irritation. A single prolonged exposure may result

in the material being absorbed in harmul amounts. Prolonged or repeated skin contact which causes the material

to be absorbed through the skin may affect the thyroid.

Eyes: May cause moderate eye irritation. Corneal injury is unlikely.

Inhalation: Mists may cause irritation of the upper respiratory tract (nose and throat). Symptoms may include

burning senstation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.

Ingestion: Single dose oral toxicity is considered to be low. Small amounts swallowed incidental to normal

handling operations are not likely to cause injury; swallowing amounts larger than that may cause injury. May

cause nausea and vomiting. May affect behavior/central nervous system (convulsions, ataxia). Prolonged or

repeated ingestion may affect thyroid.

 

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.

Special Remarks on the Products of Biodegradation: Not available.

 

Section 13: Disposal Considerations

Waste Disposal:

Waste must be disposed of in accordance with federal, state and local environmental

control regulations.

 

Section 14: Transport Information

DOT Classification: CLASS 6.1: Poisonous material.

Identification: : Toxic Liquid, organic, n.o.s. (Monothioglycerol) UNNA: 2810 PG: III

Special Provisions for Transport: Not available.

 

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: Monothioglycerol

Other Regulations:

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada): CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).

DSCL (EEC):

R21/22- Harmful in contact with skin

and if swallowed.

R36/38- Irritating to eyes and skin.

S36/37/39- Wear suitable protective clothing,

gloves and eye/face protection.

S46- If swallowed, seek medical advice

immediately and show this container or label.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0

Personal Protection: h

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Vapor respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Splash goggles.

 

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 10:52 AM

Last Updated: 11/06/2008 12:00 PM