Tween-80 MSDS


Section 1: Chemical Product and Company Identification

Product Name: Tween-80

Catalog Codes: SLP4093

CAS#: 9005-65-6

RTECS: WG2935000

TSCA: TSCA 8(b) inventory: Tween-80

CI#: Not available.

Synonym: Tween 80; Polyoxyethylene 20 sorbitan

monooleate; Polyethylene oxide sorbitan mono-oleate;

Polyoxyethylene sorbitan monooleate; Polyoxyethylene

sorbitan oleate; Sorbitan mono-9-octadecenoate

poly(oxy-1,2-ethanediyl) derivatives; Sorethytan (20)


Chemical Name: Sorbitan, monooleate polyoxyethylene


Chemical Formula: Not available.


Section 2: Composition and Information on Ingredients


Name CAS # % by Weight

Tween-80 9005-65-6 100

Toxicological Data on Ingredients: Not applicable.


Section 3: Hazards Identification

Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of


Potential Chronic Health Effects:


DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition.


Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15

minutes. Cold water may be used. Get medical attention if irritation occurs.

Skin Contact:

Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water

may be used.

Serious Skin Contact: Not available.


If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical


Serious Inhalation: Not available.


Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious

person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.

Serious Ingestion: Not available.


Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: CLOSED CUP: >148.89C (300F).

Flammable Limits: Not available.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in

presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.


Section 6: Accidental Release Measures

Small Spill:

Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.

Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority


Large Spill:

Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading water

on the contaminated surface and allow to evacuate through the sanitary system.


Section 7: Handling and Storage


Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a

fume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. If ingested, seek

medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents.


Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 32.2C (90F). Preferably

store at temperatures between 50 deg F to 90 deg. F.


Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective

threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.

Personal Protection: Safety glasses. Lab coat.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE

handling this product.

Exposure Limits: Not available.


Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Oily liquid.)

Odor: fatty (Slight.)

Taste: Not available.

Molecular Weight: Not available.

Color: Clear Amber. Yellow.

pH (1% soln/water): 7 [Neutral.]

Boiling Point: >100C (212F)

Melting Point: -20.556C (-5F)

Critical Temperature: Not available.

Specific Gravity: 1.06 - 1.10 (Water = 1)

Vapor Pressure: <0.1 kPa (@ 20C)

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, methanol.


Easily soluble in cold water, hot water. Soluble in methanol. Soluble in Toluene, alcohol, cottonseed oil, corn oil, Ethyl Acetate.

Insoluble in mineral oil.


Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Excess heat, incompatible materials

Incompatibility with various substances: Reactive with oxidizing agents.

Corrosivity: Non-corrosive in presence of glass, of stainless steel(304), of stainless steel(316).

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.


Section 11: Toxicological Information

Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 25000 mg/kg [Mouse].

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.

Special Remarks on Toxicity to Animals:

Lethal Dose/Conc 50% Kill: LD50 [Rat] - Route: Oral; Dose: 34500 ul/kg

Special Remarks on Chronic Effects on Humans:

May cause adverse reproductive effects based on animal test data. No human data found. May cause cancer based on animal

test data. No human data found. May affect genetic material (mutagenic)

Special Remarks on other Toxic Effects on Humans:

Acute Potential Health Effects: Skin: No irritation is expected, but it may cause mild/slight irritation in more sensitive

individuals. It will probably not be absorbed through the skin. Eyes: It may cause eye irritation. Inhalation: No expected to be

a health hazard. No irritation is expected to be associated with the inhalation of this material. No toxic effects are known to

be associated with the inhalation of this material. Ingestion: This material is not likely to cause irritation upon ingestion. It is

classified as "relatively harmless" by ingestion and considered to be a low ingestion hazard. Ingestion of very large doses may

cause abdominal spasms and diarrhea. Animal studies have shown it to cause cardiac changes, changes in behavior (altered

sleep time) and weight loss (upon repeated or prolonged ingestion). However, no similar human data has been reported.


Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: Not available.

Special Remarks on the Products of Biodegradation: Not available.


Section 13: Disposal Considerations

Waste Disposal:

Waste must be disposed of in accordance with federal, state and local environmental control regulations.


Section 14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.


Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: TWEEN-80

Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada): Not controlled under WHMIS (Canada).


This product is not classified according to the EU regulations. Not applicable.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 1

Reactivity: 0

Personal Protection: a

National Fire Protection Association (U.S.A.):

Health: 1

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Not applicable. Lab coat. Not applicable. Safety glasses.


Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 11:35 AM

Last Updated: 11/06/2008 12:00 PM